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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Establishing a tree shrew model of systemic lupus erythematosus and cell transplantation treatment

Fig. 6

HE staining and renal Masson and PAS staining for three groups of tree shrew organs (400× magnification). ao HE staining: a model control group showing slightly thickened alveolar septa and some alveolar atrophy, alveolar compensatory expansion, and bulla formation (arrow); b normal control group with normal lung; c treatment group without bulla formation. d model control group with diffuse hepatic cell necrosis formation (arrow) and eosinophilic bodies, granulocyte infiltration, and a large amount of liver cell degeneration; e normal control group with normal liver; f treatment group without granulocyte infiltration; g model control group showing a large amount of granulocyte infiltration in spleen red pulp (arrow); h normal control group with normal spleen; i treatment group without granulocyte infiltration; j model control group with part of the renal cyst and renal tubular cavity showing a large lightly stained mucus-like substance (arrow); k normal control group with normal kidney; l treatment group without mucus-like substance; m model control group with minor bleeding and a small amount of cardiac hypertrophy (arrow); n normal control group with normal heart; and o treatment group returned to normal without cardiac hypertrophy. pr Kidney Masson staining: p model control group with renal interstitial fibrosis (arrow; fibrosis in blue); q normal control group with normal kidney; and r treatment group with less renal interstitial fibrosis. su Kidney PAS staining: s model control group with glycogen deposition in glomeruli (arrow; glycogen dyed red–purple); t normal control group with less glycogen deposition; and u treatment group with less glycogen deposition (Color figure online)

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