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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia

Fig. 2

Functional differences between RVD AMSC expression and normal donors: VEGF secretion from AMSCs was low in RVD while HGF secretion is a higher compared to healthy controls (a). Senescence-associated DNA damage was increased in RVD patients compared to healthy individuals (b). The percentage of apoptosis was similar between RVD and healthy donors (c). AMSCS from RVD patient had lower migratory capacity compared to healthy control (d). HGF hepatocyte growth factor, RVD renovascular disease, VEGF vascular endothelial growth factor

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