Fig. 2
Micro-CT and fluorochrome-labeling histomorphometrical analysis of the repaired craniums at 8 weeks post-implantation. a Three-dimensional reconstruction and sagittal images show the different reparation effects of exosomes or tricalcium phosphate (β-TCP) only. b The bone volume/tissue volume (BV/TV) and c bone mineral density (BMD) varied between the different groups. d Fluorochrome-labeling histomorphometrical analysis of new bone formation and mineralization at 8 weeks post-operation (yellow, between 2 and 4 weeks; red, between 4 and 6 weeks; green, between 6 and 8 weeks). e Percentage of each fluorochrome area for different groups. Dunnett t test; *p < 0.05 compared with the β-TCP group, # p < 0.05 compared with the exosome (Exos) 5 × 1011 particles/mL group