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Table 1 Effect of H9N2 avian influenza virus (AIV) and mesenchymal stromal cells (MSCs) on arterial blood gas analysis of mice

From: Mesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice

Groups pH PO2 (mmHg) PCO2 (mmHg) SO2
A: Control (allantoic fluid; n = 10) 7.23 ± 0.032 90.8 ± 6.43 38.5 ± 1.66 92.7 ± 0.73
B: MSCs (1 × 105 MSCs; n = 10) 7.29 ± 0.031 88.2 ± 5.51 37.9 ± 1.11 93.8 ± 1.02
C: H9N2-infected mice (1 × 104 MID50 H9N2AIV; n = 15) 6.62 ± 0.286 46 ± 4.17* 65.34 ± 2.55* 64.82 ± 1.63*
D: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 McCoy; n = 15) 6.71 ± 0.257 48.2 ± 5.11* 64.32 ± 1.98* 68.15 ± 1.75*
E: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 MSCs; n = 15, 30 min following infection) 6.84 ± 0.613 68 ± 5.76*▲ 50.05 ± 1.09*▲ 78.47 ± 1.54*▲
F: H9N2-infected mice (1 × 104 MID50 H9N2AIV; n = 15) 6.97 ± 0.375 46 ± 4.35* 66 ± 3.34* 65 ± 2.44*
G: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 MSCs; n = 15, 1 day following infection) 6.77 ± 0.712 60 ± 3.35*▲ 52.39 ± 4.13*▲ 75.89 ± 2.44*▲
  1. *Response that is significantly different from the control (p < 0.05)
  2. ▲Response that is significantly different from the H9N2-infected mice (p < 0.05)
  3. PaCO 2 partial pressure of arterial carbon dioxide, PaO 2 partial pressure of arterial oxygen, SaO 2 saturation of arterial oxygen
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