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Table 1 Effect of H9N2 avian influenza virus (AIV) and mesenchymal stromal cells (MSCs) on arterial blood gas analysis of mice

From: Mesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice

Groups

pH

PO2 (mmHg)

PCO2 (mmHg)

SO2

A: Control (allantoic fluid; n = 10)

7.23 ± 0.032

90.8 ± 6.43

38.5 ± 1.66

92.7 ± 0.73

B: MSCs (1 × 105 MSCs; n = 10)

7.29 ± 0.031

88.2 ± 5.51

37.9 ± 1.11

93.8 ± 1.02

C: H9N2-infected mice (1 × 104 MID50 H9N2AIV; n = 15)

6.62 ± 0.286

46 ± 4.17*

65.34 ± 2.55*

64.82 ± 1.63*

D: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 McCoy; n = 15)

6.71 ± 0.257

48.2 ± 5.11*

64.32 ± 1.98*

68.15 ± 1.75*

E: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 MSCs; n = 15, 30 min following infection)

6.84 ± 0.613

68 ± 5.76*▲

50.05 ± 1.09*▲

78.47 ± 1.54*▲

F: H9N2-infected mice (1 × 104 MID50 H9N2AIV; n = 15)

6.97 ± 0.375

46 ± 4.35*

66 ± 3.34*

65 ± 2.44*

G: H9N2-infected mice + MSCs (1 × 104 MID50 H9N2AIV + 1 × 105 MSCs; n = 15, 1 day following infection)

6.77 ± 0.712

60 ± 3.35*▲

52.39 ± 4.13*▲

75.89 ± 2.44*▲

  1. *Response that is significantly different from the control (p < 0.05)
  2. ▲Response that is significantly different from the H9N2-infected mice (p < 0.05)
  3. PaCO 2 partial pressure of arterial carbon dioxide, PaO 2 partial pressure of arterial oxygen, SaO 2 saturation of arterial oxygen