Fig. 6
From: Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44
HA induces phosphorylation of Erk1/2 on DPSCs. a DPSCs were treated with HA (10 μg/mL) over a time course of 5–180 min and then examined for phosphorylation of Erk1/2 by western blotting. b DPSCs were treated with HA (10 μg/mL) in the presence of SCH772984 for 30 min, and the inhibition of Erk1/2 phosphorylation was verified. c Following inhibition of Erk1/2 phosphorylation by SCH772984 treatment, DMP-1 expression was determined by western blotting. DMP-1 dentin matrix protein-1, HA hyaluronic acid, MAPK mitogen-activated protein kinase