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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Repair of human periodontal bone defects by autologous grafting stem cells derived from inflammatory dental pulp tissues

Fig. 3

DPSCs-IPs and the therapeutic effect of Patient No. 2. a Viability of DPSCs-IPs in Patient No. 2. The proliferation status of DPSCs-IPs in Patient No. 2 was similar to that in Patient No. 1. b Mineralized nodule formation can be observed 21 days after osteogenic induction (magnification × 40). c DPSCs-IPs in Patient No. 2 were negative to hematopoietic markers, but positive to mesenchymal stem cell markers. d Mean fluorescence intensity was also calculated (*P < 0.05; ***P < 0.001). Experiments were repeated three times. e Therapeutic effect of DPSCs-IPs/β-TCP in Patient No. 2. (a) Bone defeats before the operation (red circle in Pre-Op). (b) Therapeutic effect 1 month after the operation (red circle in Post-1 M). (c) Therapeutic effect 3 months after the transplantation (red circle in Post-3 M). (d) Therapeutic effect 9 months after the operation (red circle in Post-9 M) by X-ray analysis

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