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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning

Fig. 6

Derivation of fate-committed Schwann cells by co-culture of human SCLCs with purified rat DRG neurons. Fate-committed Schwann cells were generated following 2 weeks of co-culture between human SCLCs and purified rat DRG neurons. These cells were spindle-shaped (a, d), as well as immunopositive for p75 (b, e) and S100β (c, f). Expression of human nuclear antigen (HuNeu) demonstrates that these Schwann cells were not contaminated by cells originating from rat DRGs. Numbers of p75- and S100β-immunopositive cells did not show statistical difference when comparing between normoxic and hypoxic treated groups (g). Mean ± SD, n = 3; *p < 0.05, **p < 0.01

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