Fig. 6

Nonhuman primate cells in PB and BM of NOD/SCID mice transplanted with various stages of CD34⁺ cells. Eight weeks after intravenous primate CD34⁺ transplantation in mice, primate CD45⁺, CD14⁺, and CD20⁺ cells were analyzed in the PB (a) and BM (b) of mice transplanted with unexpanded primate CD34⁺ cells, 9-day expanded CD34⁺ cells, 9-day GFP-control transduced CD34⁺ cells, and 9-day Sall4B-GFP transduced CD34⁺ cells, respectively. Normal saline was injected as the vehicle control. Data represent mean ± SD, n = 16. **P < 0.01. One-way ANOVA followed by Dunnett’s multiple comparison test. BM bone marrow, GFP green fluorescent protein, PB peripheral blood