Fig. 6

Effect of macrophages depletion in the liver fibrosis amelioration mediated by AdIGF-I-MSCs. a Representative images of Sirius Red stained-liver sections from fibrotic mice treated with saline, saline + LipClod, AdIGF-I-MSCs or AdIGF-I-MSCs + LipClod 2 weeks after treatments. b Morphometric analyses of Sirius Red-positive area. c mRNA expression levels of Col1A2 and d α-SMA in liver samples. ANOVA Tukey’s post-test; ^** p < 0.01, ^*** p < 0.001 and ^**** p < 0.0001 vs. saline; ^σ p < 0.05 vs AdIGF-I-MSCs + LipClod; ^τ p < 0.05, ^ττ p < 0.01, ^τττ p < 0.001, ^ττττ < 0.0001 vs. saline + LipClod