Fig. 7

Regulation of cell cycle-related genes by AdIGF-I-MSCs treatment. a Screening analyses of mRNA expression profile differences in between fibrotic liver samples after saline (control) or AdIGF-I-MSCs treatments, using a functionally specific qPCR array. Punctated lines represent the thresholds; genes with scores above them were considered as differentially regulated (induced: to the right; repressed: to the left) by AdIGF-I-MSCs. b-g Changes in the most differentially regulated genes were validated by qPCR, and comparisons against AdGFP-MSCs condition were added. ANOVA Tukey’s post-test, **p < 0.01 and ****p < 0.0001 vs. saline; ^σ p < 0.05; ^σσ p < 0.01; ^σσσ p < 0.001 and ^σσσσ p < 0.0001 vs. AdGFP-MSCs