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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human fetal and adult epicardial-derived cells: a novel model to study their activation

Fig. 4

Fetal and adult EPDCs have a different migration ability upon TGFβ stimulation. a In a scratch assay, both fetal and adult EPDCs closed the gap as a sheet of cells (scale bar: 100 μm). Quantification of the migration rate after 12 hours showed that, (b) upon TGFβ stimulation and thereby partial induction of EMT, the percentage closure decreased for fetal EPDCs (paired t test). On the other hand, (c) adult EPDCs closed the gap faster upon TGFβ stimulation (paired t test). The different colors represent the different donors, for both fetal and adult cultures. # p < 0.05. EPDCs epicardial-derived cells, SB medium containing SB431542, TGFβ transforming growth factor beta

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