Fig. 3

miR-140 suppresses the migratory and invasive potentials of CRC cells. a, b and c CRC cells were first transfected with the miRNA mimics or siRNAs. Cell migratory and invasive potentials were then determined by the scratch-wound assay and transwell chamber assays with or without matrigel. d, e and f Similarly, scratch-wound assay and transwell assays with or without matrigel were used to determine the potential for migration and invasion in the miR-140 knockdown CRC cells. The representative pictures were chosen from three independent experiments. The cell numbers passing through the filter are indicated as mean ± SD. *P < 0.05