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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: RETRACTED ARTICLE: microRNA -140-5p inhibits colorectal cancer invasion and metastasis by targeting ADAMTS5 and IGFBP5

Fig. 4

ADAMTS5 and IGFBP5 are inversely correlated with the expression of miR-140 and positively correlated with the tumor stage and metastasis of CRC. a qRT-PCR analysis of ADAMTS5 and IGFBP5 expressions in 60 pairs of CRC and adjacent nontumorous tissues. b Correlation of ADAMTS5 and IGFBP5 and miR-140 expression was analyzed by Spearman correlation test in CRC tissues. c Immunohistochemistry analysis of ADAMTS5 and IGFBP5 expressions in CRC tissues. 1, 2, 5 and 6: magnification × 20; and 3, 4, 7 and 8: magnification × 40; 1, 3, 5 and 7: primary sites of tumor tissue; and 2, 4, 6 and 8: noncancerous region of CRC. Scale bar = 100 μm. The results of immunohistochemistry were evaluated by the staining scores. *P < 0.05

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