Skip to main content
Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Bile acid: a potential inducer of colon cancer stem cells

Fig. 6

DCA/LCA increased the expression and activation of EGFR in HCoEpiC. Real-time qPCR showing increased expression of EGFR mRNA in cells in response to DCA and LCA (a). Western blot analysis indicates increased tyrosine phosphorylation (Y992) of EGFR in response to DCA (b). Real-time qPCR showing changes in the expression of the MMPs in cells in response to DCA or LCA (c). Results represent the mean of three separate determinations ± standard deviation. ***P <0.001, compared with control. DCA (deoxycholic acid), EGFR (epidermal growth factor receptor), LCA (lithocholic acid), MMP (matrix metallopeptidase)

Back to article page