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Table 1 Strategic mode of directing the fate of stem cells through nanotopography of the synthetic scaffolds

From: Nanostructured scaffold as a determinant of stem cell fate

No.

Cells

Scaffolds

Differentiated cell type

1

Rat hair follicle stem cells (HFSCs)

Aligned poly-ε-caprolactone (PCL) nanofiber

Neuronal lineage

2

Mouse embryonic stem cells (ESCs)

Poly-l-lactic acid (PLLA) nanofiber

Osteogenic lineage

3

Retinal progenitor cells (RPCs)

Microfabricated PCL

Differentiated RPC

4

Mouse ESCs

Aligned PCL nanofibers

Neuronal lineage

5

Human mesenchymal stem cells (MSCs)

Type 1 collagen nanofiber

Osteogenic differentiation

6

Human MSCs

Poly(lactide-co-glycolide) nanofiber

Osteogenic lineage

7

Rat mesenchymal stem cells (MSCs)

PCL nanofiber

Osteogenesis

8

Human MSCs

Polydimethylsiloxane (PDMS) nanogroove

Neuronal lineage

9

Human MSCs

Polyacrylamide hydrogel

Neuronal lineage

10

Rat hippocampal progenitor cells

Micropatterned polystyrene with laminin

Neuronal lineage