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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling

Fig. 3

Inhibition of endothelial nitric oxide synthase (eNOS) through l-NG-nitroarginine methyl ester (l -NAME) treatment downregulates eASC osteogenic differentiation. Relative mRNA transcripts analysis by qPCR showing that 2 mM l-NAME treatment decreased the expression of osteoblast markers a alkaline phosphatase (ALP) and b Runx2 in eNOS transduced eASCs compared to untreated eNOS transduced cells. *p < 0.05, versus eNOS (l-NAME), eASC (osteogenic induction), and eASC (growth medium)

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Stem Cell Research & Therapy

ISSN: 1757-6512