Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis

Fig. 5

Downregulation of Tid1 impairing mitochondrial activity and ATP concentration. a Mouse C2C12 cells were first infected with lentiviral virus (Control: sh-luc; shRNAi-Tid1: sh-Tid1-439 and sh-Tid1-889) to downregulate the Tid1 expression, and the images were acquired before the induced differentiation (BD) and on day 3 after the induced differentiation (D3). b, c Confocal images of Mito Tracker staining (b) and JC-1 staining (c) (indication of mitochondrial membrane potential) of the control and Tid1-knockdown C2C12 before induced differentiation were collected. d The intracellular ATP concentration of control and Tid1-knockdown C2C12 before the induced differentiation were measured. ***P < 0.001

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512