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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Extracellular matrix components and culture regimen selectively regulate cartilage formation by self-assembling human mesenchymal stem cells in vitro and in vivo

Fig. 4

Biochemical quantification of glycosaminoglycan (GAG), collagen (COL) and cellular (DNA) contents. a Comparisons of type I collagen (Col1) discs, type II collagen (Col2) discs and pellets after 17 days or 42 days of chondrogenic induction. At day 42, pellets exhibited higher GAG and DNA contents (per wet weight) and discs exhibited higher COL/DNA and COL/GAG ratios; Col1 discs had higher GAG and DNA contents than Col2 discs. b Comparisons of Col1 discs at different seeding densities. Doubling seeding density from 0.5 × 106 to 1.0 × 106 increased GAG content (per wet weight) but not COL content. Only successfully formed discs were evaluated in the Col1 and Col2 groups

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Stem Cell Research & Therapy

ISSN: 1757-6512