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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

Fig. 6

Comparison of the common developmental genes observed at day 14 in all three cell lines in the absence of valproic acid (VPA) with the VPA-deregulated genes at day 14 in each cell line (absolute fold change > 2, false discovery rate-corrected p value < 0.05). a Overlap of the developmental upregulated genes with the VPA-induced downregulated genes (four genes; see C for fold changes). b Overlap of developmental downregulated genes with the VPA-induced upregulated genes (11 genes; see D and E for fold changes). c Fold change values for B3GALNT1, 233944_at, DOK6, and BCL2 for all three cell lines. d Fold change values for C9orf135, GPR176, LRAT, NFE2L3, MICB, HSPA2, and CLDN10 for all three cell lines. e Fold change values for PFKP, PRKCB, CD9 and OGDHL for all three cell lines

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Stem Cell Research & Therapy

ISSN: 1757-6512