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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: The lncRNAs involved in mouse airway allergic inflammation following induced pluripotent stem cell-mesenchymal stem cell treatment

Fig. 5

The nine lncRNAs were co-expressed with mRNAs, which were enriched in the immune response. a Pearson’s correlation coefficient of 72 mRNAs (vertical axis) involved in inflammatory cytokines and receptors, together with 23 screened-out lncRNAs was taken. Nine lncRNAs (horizontal axis) were isolated, in which >40 co-expressed mRNAs were selected. Pearson’s correlation coefficients >0.6 or < –0.6, and p values <0.05 were considered correlative. Red represents a co-expressed pair, and white does not. b The co-expression network was established between the selected nine lncRNAs and 96 mRNAs. The red nodes denote lncRNAs, and the green nodes denote mRNAs. Pearson’s correlation coefficients >0.6 or < –0.6, and p values <0.05 were considered correlative. c GO and pathway analyses of 96 mRNAs co-expressed with lncRNAs were performed. The ontology covers three domains: biological process, cellular component, and molecular function. The top five significant GO categories and pathways are shown

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