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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Synergistic antibacterial effect of co-administering adipose-derived mesenchymal stromal cells and Ophiophagus hannah l-amino acid oxidase in a mouse model of methicillin-resistant Staphylococcus aureus-infected wounds

Fig. 5

Wound biopsies of methicillin-resistant Staphylococcus aureus (MRSA)-infected study groups were homogenized and plated on CHROMagar for enumeration of mauve colonies. All treatment groups demonstrated reduction of bacterial load compared to the untreated (phosphate-buffered saline; PBS) control. The most significant reduction was observed in the standard antibiotic group (Fusidic acid ointment; FAO). In the experimental therapy groups, the mesenchymal stromal cells (MSCs) and Ophiophagus hannah l-amino acid oxidase (Oh-LAAO) combinational treatment resulted in the highest reduction of MRSA count, by approximately two orders of magnitude. MRSA enumeration of the study groups with individual treatment of MSCs and Oh-LAAO indicated a reduction of one order of magnitude compared to the untreated control

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Stem Cell Research & Therapy

ISSN: 1757-6512