Skip to main content

Table 1 Wound area assessment at days 3 and 7 of in vivo study and histopathological scores of healing parameters performed on biopsy samples sectioned and stained by hematoxylin and eosin and Masson’s trichrome

From: Synergistic antibacterial effect of co-administering adipose-derived mesenchymal stromal cells and Ophiophagus hannah l-amino acid oxidase in a mouse model of methicillin-resistant Staphylococcus aureus-infected wounds

  

% Wound area

Treatment

Histological score

Day 3

Day 7

MRSA-infected

 MSCs and Oh-LAAO

9.8 ± 0.6

65.8 ± 3.8

43.3 ± 3.2

 MSCs

6.1 ± 0.5

82.1 ± 2.1

57.8 ± 2.2

 Oh-LAAO

5.7 ± 0.3

83.9 ± 2.3

58.9 ± 2.1

 FAO

6.4 ± 0.3

75.5 ± 2.5

51.9 ± 2.1

 PBS

3.7 ± 0.4

91.3 ± 2.9

65.3 ± 3.1

Uninfected

 MSCs and Oh-LAAO

11.3 ± 0.5

58.9 ± 3.8

40.1 ± 3.2

 MSCs

11.5 ± 0.3

55.6 ± 3.9

38.9 ± 4.2

 Oh-LAAO

6.6 ± 0.7

74.1 ± 4.8

51.5 ± 3.9

 FAO

6.7 ± 0.5

73.3 ± 4.5

50.9 ± 3.7

 PBS

6.9 ± 0.4

71.8 ± 4.7

50.3 ± 3.5

  1. FAO Fusidic acid ointment, MSCs mesenchymal stromal cells, Oh-LAAO Ophiophagus hannah l-amino acid oxidase, PBS phosphate-buffered saline