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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Immunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis

Fig. 6

Effect of MPC treatment on cartilage erosion in the sheep CIA model. The cartilage on the surface of the talus was assessed macroscopically using a 5-point scale based on the OARSI recommendations for macroscopic scoring of cartilage pathology, as described in the Methods section. Values were compared between the MPC-treated and the control group using paired Wilcoxon (left and right) and unpaired Mann-Whitney (saline and MPC treatment) tests. Lines represent mean ± SEM of seven to eight sheep. ** represents significant difference; p ≤ 0.01. MPC mesenchymal precursor cells

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