Fig. 8

A Effect of MPC treatment on the number of inflammatory cells in SMs from sheep with CIA. Lines represent median and interquartile ranges of seven to eight sheep. Frozen sections were immunostained for CD4 (a), CD8 (b), γδ TCR (c), CD79a (d), CD14 (e) and Ki-67 (f). Blood vessels were identified by vWF expression (g). The data were compared using paired Wilcoxon (left and right) and unpaired Mann-Whitney (saline and MPC treatment) tests. Lines represent mean ± SEM of six to eight sheep with ^* and ^** representing p ≤ 0.05 and p ≤ 0.01, respectively. B Immunohistology of synovial membranes from arthritic hock joints following saline (left column) or MPC (right column) treatment. The frozen sections were stained with antibodies to CD4 (a , b), CD8 (c , d), γδTCR (e , f), CD79a for B cells (g , h) and CD14 (i , j). The bars represent 25 μm. MPC mesenchymal precursor cells