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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Integrated analysis of hematopoietic differentiation outcomes and molecular characterization reveals unbiased differentiation capacity and minor transcriptional memory in HPC/HSC-iPSCs

Fig. 2

HPC/HSC-iPSCs showed unbiased differentiation potential into hematopoietic progenitor cells. a Schematic illustration of the flow cytometry analysis. b Typical cell morphology of ESCs and iPSCs co-cultured with OP9 stromal cells. Left, bright field; GFP, the field under fluorescence microscopy with an excitation peak of 488 nm. c Expression of SSEA-1 by ESCs and iPSCs as detected using flow cytometry after co-culture with OP9 stromal cells for 8 days. Error bars indicate the SD P, P value, unpaired t test. d Differentiation efficiency of ESCs and iPSCs into different types of hematopoietic progenitor cells; Error bars indicate the SD P, P value, unpaired t test. HPC/HSC hematopoietic progenitor and stem cell, iPSC induced pluripotent stem cell, SD standard deviation

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