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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Administration of multipotent mesenchymal stromal cells restores liver regeneration and improves liver function in obese mice with hepatic steatosis after partial hepatectomy

Fig. 4

Donor MSCs persist and proliferate in the liver of 70% hepatectomized mice. Normal and obese mice received 5 × 105 MSCsGPF post-Hpx. Two, 10 and 30 days later, the presence of donor cells was evaluated by GFP immunoreactivity (Alexa Fluor 488 – green), nuclei were counterstained with DAPI (blue). a Representative micrographs of donor MSCsGFP in the liver parenchyma. MSC proliferation in hepatic tissue was evaluated by PCNA immunoreactivity (Alexa Fluor 555 – red). b Representative micrographs of MSCsGFP proliferation 30 days after their administration

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