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Table 1 The comparison of hESC-CMs with hiPSC-CMs

From: Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes

Drug hESC-CMs hiPSC-CMs
CI (μmol•L-1) IC50/EC50 (μmol•L-1) CI (μmol•L-1) IC50/EC50 (μmol•L-1)
E-4031 0.01↑ 0.02 0.1↓ 0.04
Isoprenaline 0.1↓ 0.04 1↓ 0.03
Quinidine 100↓ 2.18 100↓ 13.97
Haloperidol NO 0.14 10↓ 5.17
  1. CI cell index, hESC-CMs human embryonic stem cells-derived cardiomyocytes, hiPSC-CMs human induced pluripotent stem cells-derived cardiomyocytes