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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury

Fig. 3

Renal analysis on D2. a Plasma urea over time after IRI surgery. b AQP2: immunoblots and densitometric analysis of samples from control (n = 2), IRI (n = 5) and IRI + huMSC (n = 7) rats, on D2. c Representative light microscopy of periodic acid–Schiff staining and proportional acute tubular damage and mean renal damage scores in IRI and IRI + huMSC rats, on D2 (magnification, ×4). d Photomicrographs and bar graphs showing CD68-positive cells (arrows) in the tubulointerstitium in control, IRI and IRI + huMSC rats, on D2 (magnification, ×40). e TGF-β1: immunoblots and densitometric analysis of samples from control (n = 2), IRI (n = 5) and IRI + huMSC (n = 7) rats, on D2. f Photomicrographs and bar graphs showing CD3-positive cells (arrows) in the tubulointerstitium in control, IRI and IRI + huMSC rats, on D2 (magnification, ×40). a p < 0.05 vs control. b p < 0.05 vs IRI + huMSC. huMSC human umbilical cord-derived mesenchymal stromal cell, IRI ischaemia/reperfusion injury, TGF- β transforming growth factor beta, AQP2 aquaporin

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