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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury

Fig. 4

Densitometric analysis and immunoblotting of markers of stress-induced senescence in kidney tissue in control (n = 2), IRI (n = 5) and IRI + huMSC (n = 7) rats, on D2. a Immunoblots and densitometric analysis of Klotho. b Immunoblots and densitometric analysis of β-gal. c Immunoblots and densitometric analysis of HO-1. d Immunoblots and densitometric analysis of MnSOD. e Bar graphs showing renal miR-29a expression. f Bar graphs showing renal miR-34a expression. g Bar graphs showing renal miR-29b expression. h Bar graphs showing renal miR-335 expression. i Immunoblots and densitometric analysis of p21. j Immunoblots and densitometric analysis of p16. a p < 0.05 vs control. b p < 0.05 vs IRI + huMSC. c p = 0.05 vs control. d p = 0.05 vs IRI + huMSC. huMSC human umbilical cord-derived mesenchymal stromal cell, IRI ischaemia/reperfusion injury, β-gal β-galactosidase, MnSOD manganese superoxide dismutase, HO-1 heme oxygenase-1

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Stem Cell Research & Therapy

ISSN: 1757-6512