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Table 1 Renal function on day 2 after ischaemia/reperfusion

From: Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury

Parameter Control IRI IRI + huMSC
Urea (mg/dl) 52 ± 2.5 234 ± 36.3a,b 108 ± 19.6
Creatinine (mg/dl) 0.3 ± 0.02 2.4 ± 0.4a,b 0.9 ± 0.17
Creatinine clearance (ml/min/100 g BW) 0.59 ± 0.04 0.10 ± 0.02a,b 0.23 ± 0.05a
FENa (%) 0.10 ± 0.01 3.27 ± 1.10a,b 0.48 ± 0.09
Urinary flow rate (ml/min/100 g BW) 0.002 ± 0.0004 0.005 ± 0.0006a 0.006 ± 0.0007a
  1. IRI ischaemia/reperfusion injury (rats submitted to renal artery clamping for 45 min, followed by 6 h of reperfusion), IRI + huMSC IRI + human umbilical cord-derived mesenchymal stromal cells (rats submitted to IRI and subsequently treated with huMSCs), BW body weight, FENa fractional excretion of sodium
  2. a p < 0.05 vs control
  3. b p < 0.05 vs IRI + huMSC