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Table 3 Renal function on day 49 after ischaemia/reperfusion

From: Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury

Parameter

IRI

IRI + huMSC

Urea (mg/dl)

65 ± 26.7a

52 ± 5.0

Creatinine (mg/dl)

0.9 ± 0.26a

0.6 ± 0.03

Creatinine clearance (ml/min/100 g BW)

0.29 ± 0.08

0.42 ± 0.1

FENa (%)

0.07 ± 0.03a

0.03 ± 0.01

Urinary flow rate (ml/min/100 g BW)

0.002 ± 0.0009

0.005 ± 0.0013

  1. IRI ischaemia/reperfusion injury (rats submitted to renal artery clamping for 45 min, followed by 6 h of reperfusion), IRI + huMSC IRI + human umbilical cord-derived mesenchymal stromal cells (rats submitted to IRI and subsequently treated with huMSCs), BW body weight, FENa fractional excretion of sodium
  2. a p < 0.05 vs IRI + huMSC