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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury

Fig. 1

Effect of different renal stem/progenitor cells and their derived EVs in IRI mice: functional evaluation. a Serum creatinine and b BUN values at day 2 after IRI, in mice injected with vehicle alone (IRI-CTL), 1 × 105 Gl-MSCs (IRI-Gl-MSC), 400 × 106 EVs produced by Gl-MSCs (IRI-Gl-MSC-EV), 400 × 106 EVs produced by Gl-MSCs and obtained by floating process (IRI-Gl-MSC-EV-float), 400 × 106 EVs produced by Gl-MSCs and treated with RNase (IRI-RNase-Gl-MSC-EV), 1 × 105 T-CD133+ cells (IRI-T-CD133 +), 480 × 106 EVs produced by T-CD133+ cells (IRI-T-CD133 + -EV), 230 × 106 EVs derived from fibroblasts (IRI-F-EV), in healthy (normal) and in sham-operated SCID mice. Data are expressed as mean ± SD, ANOVA with Dunnett’s multiple comparison test were performed (* p < 0.05)

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