Fig. 5

Characterization of EV RNA content. Representative bioanalyzer profiles, showing the size distribution of total RNA extracted from Gl-MSCs and Gl-MSC-EVs. The first peak (left side of each panel) represents an internal standard. The two peaks of ribosomal RNA 18S and 28S are detectable in cells (a) and barely detectable in the corresponding EVs (b). EVs exhibited a relevant peak of small RNAs. After treatment with RNase A (c), RNAs inside EVs were degraded