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Table 1 Cardiac function of experimental groups

From: Cardiosphere-derived cells do not improve cardiac function in rats with cardiac failure

   Experimental group
Parameter Time (days) Sham (n = 8) Placebo (n = 9) hCDC (n = 11) rCDC (n = 10)
Ejection fraction (%) –1 76.85 ± 4.24 75.50 ± 1.48 79.83 ± 5.34 72.97 ± 3.69
59 70.72 ± 2.08 32.88 ± 6.28* 31.48 ± 7.26* 30.39 ± 6.97*
90 69.33 ± 5.45 34.49 ± 9.48* 31.26 ± 7.66* 29.56 ± 7.59*
120 69.44 ± 5.36 34.62 ± 11.08* 30.89 ± 6.39* 28.58 ± 7.68*
End-diastolic volume (μl) –1 358.8 ± 68.61 383.7 ± 80.47 323.2 ± 39.71 357.7 ± 65.29
59 424.4 ± 97.15 643.1 ± 98.04* 712.3 ± 137.9* 656.8 ± 213.1*
90 438.7 ± 110.40 730.6 ± 172.90* 833.3 ± 234.3* 736.3 ± 259.8*
120 467.7 ± 108.2 736.20 ± 161.6* 830 ± 243.9* 840.2 ± 313.4*
End-systolic volume (μl) –1 80.91 ± 22.78 93.20 ± 25.63 69.52 ± 16.13 96.06 ± 18.68
59 121.4 ± 28.45 382.4 ± 105.2* 502 ± 135.8* 464.40 ± 179.3*
90 137.5 ± 50.67 488.80 ± 160.5* 609.2 ± 244.8* 525 ± 212.6*
120 142 ± 34.97 492.5 ± 163.6* 551 ± 214.9* 591.40 ± 271.3*
Fractional area change (%) –1 71.38 ± 11.53 67.38 ± 9.06 73.75 ± 8.34 66.05 ± 8.87
59 66.58 ± 7.23 30.22 ± 10.12* 25.15 ± 11.40* 24.90 ± 10.79*
90 63.95 ± 19.47 25.70 ± 9.56* 20.78 ± 10.16* 25.85 ± 8.36*
120 57.33 ± 11.30 27.71 ± 20.11* 29.65 ± 11.46* 25.47 ± 9.69*
  1. Data presented as mean ± SD. Day –1 shows baseline values (before myocardial infarction) for all groups. Day 59 shows data 1 day before treatment with placebo, hCDC, or rCDC
  2. *p < 0.05 compared with sham-operated group
  3. hCDC human cardiosphere-derived cell, rCDC rat cardiosphere-derived cell