Variable
|
Total
|
Control group
|
hADSC-treated group
|
p
|
---|
Wexner score (mean ± SD)
|
Baseline
|
8.17 ± 3.74
|
6.0 ± 1.18
|
10.33 ± 0.87
|
0.02*
|
Post intervention
|
4.56 ± 3.22
|
2.67 ± 0.62
|
6.44 ± 1.08
|
0.36#
|
Standardized mean difference (95% confidence interval)a
|
3.73 (2.61–4.86)
|
3.63 (2.0–5.07)
|
3.97 (2.31–5.62)
|
0.41
|
Percentage of muscle occupied area (mean ± SD)
|
15.25 ± 7.34
|
11.65 ± 7.74
|
18.85 ± 5.06
|
0.02*
|
Electromyography recording (n, %)
|
Negative
|
10 (58.82)
|
9 (100.0)
|
1 (12.50)
|
0.002*
|
Positive
|
7 (41.18)
|
0 (0.0)
|
7 (87.50)
| |
-
Control group sphincteroplasty alone, hADSC-treated group human adipose-derived stem cells + sphincteroplasty, SD standard deviation
-
aBased on Hedge’s g
- *Based on Mann–Whitney U test
-
#Based on nonparametric ANCOVA test