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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells

Fig. 6

Histomorphological analysis of distant organs to assess ectopic cell distribution. The lung and the kidney were evaluated by histology and immunohistochemistry (IHC) to test the occurrence of ectopic distribution of human cell emboli. With respect to the lung (a), hematoxylin and eosin (H&E) staining revealed normal histomorphological aspects. Few and scattered human mitochondria positive cells (arrows) were observed, without differences in their numbers between animals transplanted with uncoated versus HA-coated hBTSCs (a). Also the kidney appeared invariably normal (b) with respect to the histomorphological aspects; no human Hep-Par1+ cells were identified by IHC. HA hyaluronan, hBTSC human biliary tree stem cells

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Stem Cell Research & Therapy

ISSN: 1757-6512