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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Netrin-1 acts as a non-canonical angiogenic factor produced by human Wharton’s jelly mesenchymal stem cells (WJ-MSC)

Fig. 4

Netrin-1, secreted by WJ-MSC, promotes angiogenesis in HUVEC. a Representative images of HUVEC tubule assay treated as indicated. Cells were exposed for 4 h to DMEM, endothelial growth media (EGM), WJ-MSC-conditioned media (CM), 2F5 [a drug targeting Netrin-1 (NTN-1), 0.5 μg/μL] and CBO (a VEGF-receptor inhibitor, 20 μM), scale bar = 15 μm. b Quantified data correspond to the mean ± S.E.M. (n = 3, * p < 0.05 vs. DMEM, β p < 0.05 vs. EGM, Φ p < 0.05 vs. CM)

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