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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: CD117+CD44+ Stem T Cells Develop in the Thymus and Potently Suppress T-cell Proliferation by Modulating the CTLA-4 Pathway

Fig. 6

CTLA-4 correlates with CD44 expression in different populations of CD117-positive thymocytes. Thymocytes were treated as indicated in Methods and analyzed by flow cytometry. a CTLA-4 expression in CD4+CD117+CD44+ cells. b CTLA-4 expression in CD8+CD117+CD44+ cells. c CTLA-4 expression in DNCD117+CD44+ cells. Data show mean percent of total cells ± SD from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001. DN double-negative

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