Skip to main content
Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Human amnion epithelial cells rescue cell death via immunomodulation of microglia in a mouse model of perinatal brain injury

Fig. 8

Soluble factors from hAEC protect microglia after LPS stimulation. a Following 24 h of LPS stimulation, 48-h exposure to hAEC-conditioned medium significantly increased the percentage of live microglia and reduced the percentage of apoptotic microglia. b Representative FACS plots demonstrating the shift of microglia into Q4 (Annexin-V+ PI). Q1 necrotic cells, Q2 late apoptotic or dead cells, Q3 live cells, Q4 early apoptotic cells. *p < 0.05, Student’s t test. hAEC human amnion epithelial cell, CM conditioned medium

Back to article page