Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Knockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells

Fig. 4

Slc41a1 knockdown elevated MGP expression. a, b Mgp gene expression of control (ctrl) mMSCs and Slc41a1-knockdown mMSCs (KD) with normal and high extracellular magnesium concentration before and 3, 6, and 9 days after the osteogenic induction (D0, D3, D6, D9). Data normalized by the gene expression of undifferentiated ctrl and KD MSCs respectively (D0) (N = 3, n = 3). c Mgp gene expression of control and Slc41a1 KD-mMSCs with normal extracellular magnesium concentration. Data normalized by Mgp gene expression of undifferentiated control MSCs (D0) (N = 3, n = 3). d Extracellular secreted MGP concentration obtained by ELISA assay (N = 3, n = 3). MGP matrix gla protein. * p< 0.05

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512