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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study

Fig. 3

Radiological analyses. a X-ray photographic analysis to show the changes and evolution of periapical tissues and apical and/or lateral dentin formation in the root canal at the first visit (FV), pre-transplantation just before cell transplantation (Pre), and 4, 12, and 24/28 weeks (wks) after autologous transplantation of MDPSCs with G-CSF in pulpectomized teeth in five patients. No significant changes were seen in the periapical areas, except in patient 4 who showed widening of periodontal ligament space at 12 weeks and periapical radiolucency at 24 and 32 weeks. Patient 2 preoperatively had periapical radiolucent lesion decreased in area size with a little radiographic periodontal ligament space widening at 24 weeks. b Cone beam computed tomography evaluation of apical/lateral dentin formation in the root canal in coronal and axial slices in three patients at 16 and 28/32 weeks. Arrows indicate newly formed dentin. The 3D cone beam computed tomography images by the OsiriX program demonstrated a decrease in low-density areas at 28 weeks compared with 16 weeks

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