Fig. 2

Chick CAM model of angiogenesis. a Immunohistochemical (IHC) score for vWF staining. Each sample was analyzed double blind and independently by two investigators. Staining (brown) was semiquantitatively scored as 0, 1, 2 or 3 for absence, weak, moderate and strong staining, respectively. b–e Representative macroscopic pictures of 48-h incubated matrigel scaffolds in the in-vivo CAM assay. f–i Representative immunochemical staining of vWF in sections of matrigel–CAM junction. *p < 0.05 vs PBS, CM and ASCs; †p < 0.05 vs PBS. ASC adipose-derived mesenchymal stem cell, CM conditioned media, PBS phosphate-buffered saline