Table 1 MRI analysis of cardiac performance and scar size
Baseline (1 week post MI) | 1 week post infusion (2 weeks post MI) | 3 weeks post infusion (4 weeks post MI) | ||
|---|---|---|---|---|
LVEF (%) | PBS | 48.4 (48.3–50.1) | 48.9 (46.6–50.7) | 46.5 (46.3–48.1)* |
ASCs | 47.7 (47.6–54.2) | 48.3 (47.5–54.1) | 48.7 (47.1–49.7) | |
CM | 47.2 (46.5–47.5) | 48.2 (48.0–49.4) | 49.5 (48.2–52.1) | |
ASCs + CM | 50.0 (46.4–53.0) | 49.5 (48.7–51.0) | 47.6 (47.3–49.6) | |
LVEDV (ml) | PBS | 91.9 (85.3–94.1) | 107.5 (101.0–109.1)* | 118.7 (115.0–125.7)*† |
ASCs | 113.0 (105.0–116.0) | 123.2 (101.3–124.3) | 121.0 (117.3–129.3) | |
CM | 87.7(81.9–122.8) | 93.4 (89.0–94.1)* | 119.2 (106.1–122.3) | |
ASCs + CM | 91.4 (89.0–98.4) | 93.7 (84.0–124.4) | 136.32 (82.1–153.0) | |
LVESV (ml) | PBS | 44.0 (40.0–46.2) | 55.2 (46.1–58.3) | 63.4 (45.0–65.2)† |
ASCs | 55.0 (49.9–60.7) | 64.4 (51.4–64.9) | 62.3 (60.6–66.0) | |
CM | 42.9 (40.9–64.8) | 47.2 (46.0–49.4) | 60.2 (47.5–61.5) | |
ASCs + CM | 46.1 (40.4–50.3) | 48.0 (42.0–49.5) | 64.8 (43.3–77.0) | |
Scar size (g) | PBS | 11.6 (10.5–12.4) | 10.8 (10.1–13.2) | 10.4 (9.8–11.7) |
ASCs | 9.9 (9.0–16.1) | 9.5 (9.4–13.9) | 10.8 (9.6–14.4) | |
CM | 11.3 (9.7–13.2) | 10.1 (9.2–11.0) | 9.5 (8.1–9.9) | |
ASCs + CM | 13.0 (10.0–15.0) | 12.3 (10.2–14.0) | 10.8 (7.2–11.5) | |