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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

Fig. 5

IHC analysis. a Collagen II staining. Staining of cartilage (brown coloration) in the normal, iMSC-Exos, and SMMSC-Exos groups was stronger than in the OA group. In the SMMSC-Exos group, collagen II expressed very weakly at the superficial zone compared with the iMSC-Exos group. b Collagen I staining. Collagen I expression was not found in the cartilage of the normal, iMSC-Exos, and SMMSC-Exos groups, but was present in the OA group. iMSC-Exos exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells, OA osteoarthritis, SMMSC-Exos exosomes secreted by synovial membrane mesenchymal stem cells

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