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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism

Fig. 5

Immunohistochemistry (IHC) analysis for cytokines HGF, VEGF, and IGF-1 in ovaries after hUCMSCs transplantation. Images for control group treatment group and normal control group at three time points are listed. A brown-yellow coloring of the cytoplasm of the cells was deemed to be positive staining. It can be seen that treatment with hUCMSCs enhanced HGF, VEGF, and IGF-1 expression in ovaries. Scale bar = 200 um. HGF hepatocyte growth factor, IGF-1 insulin-like growth factor-1, VEGF vascular endothelial cell growth factor

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