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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: DNA double-strand breaks in human induced pluripotent stem cell reprogramming and long-term in vitro culturing

Fig. 5

The time-course showing the recovery of human dermal fibroblasts (hDFs) and hiPSCs (a,b) or hESCs (c,d) after 1 Gy of γ-irradiation. a,c Number of DSBs recognized by γH2AX and b,d by p53-binding protein 1 (53BP1) in the untreated control (0 h) and at 0.5 h, 2 h, and 6 h after irradiation with 1 Gy. The results are shown in the EdU-negative population. The mean value of the DSBs was calculated for each of the three regions on the slide. The error bar indicates the SEM

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