Non-irradiated control cells | Irradiated cells (1Gy) | |||||||
---|---|---|---|---|---|---|---|---|
G1 (EdU-negative cells) | S/G2 (EdU-positive cells) | G1 (EdU-negative cells) | S/G2 (EdU-positive cells) | |||||
No. of foci ± SEM | No. of cells | No. of foci ± SEM | No. of cells | No. of foci ± SEM | No. of cells | No. of foci ± SEM | No. of cells | |
hDF | ||||||||
γH2AX | 1.13 ± 0.11 | 463 | 29.9 ± 1.32 | 60 | 19.89 ± 0.36 | 485 | 45.49 ± 0.88 | 97 |
53BP1 | 1.49 ± 0.07 | 486 | 19.64 ± 1.23 | 80 | 15.55 ± 0.22 | 501 | 19.20 ± 0.91 | 69 |
CBIA-3 low | ||||||||
γH2AX | 5.56 ± 0.22 | 464 | 22.98 ± 0.38 | 523 | 21.87 ± 0.34 | 612 | 28.71 ± 0.34 | 554 |
53BP1 | 2.13 ± 0.12 | 445 | 8.76 ± 0.35 | 407 | 19.01 ± 0.31 | 552 | 23.1 ± 0.42 | 496 |
CBIA-3 high | ||||||||
γH2AX | 4.42 ± 0.20 | 483 | 17.91 ± 0.41 | 337 | 8.01 ± 0.27 | 594 | 7.97 ± 0.35 | 480 |
53BP1 | 1.46 ± 0.07 | 625 | 4.73 ± 0.18 | 510 | 14.45 ± 0.29 | 551 | 13.66 ± 0.31 | 447 |
CBIA-5 low | ||||||||
γH2AX | 5.69 ± 0.23 | 542 | 25.1 ± 0.47 | 415 | 28.6 ± 0.52 | 437 | 41.00 ± 0.55 | 421 |
53BP1 | 4.03 ± 0.18 | 445 | 15.3 ± 0.49 | 425 | 17.84 ± 0.26 | 613 | 23.32 ± 0.30 | 642 |
CBIA-5 high | ||||||||
γH2AX | 2.98 ± 0.13 | 520 | 10.98 ± 0.26 | 508 | 11.57 ± 0.27 | 445 | 24.45 ± 0.39 | 480 |
53BP1 | 1.56 ± 0.07 | 608 | 4.71 ± 0.21 | 461 | 8.04 ± 0.17 | 490 | 10.84 ± 0.20 | 514 |
CBIA-7 low | ||||||||
γH2AX | 5.89 ± 0.25 | 382 | 23.77 ± 0.45 | 414 | 26.48 ± 0.44 | 511 | 36.71 ± 0.52 | 444 |
53BP1 | 2.73 ± 0.13 | 487 | 10.42 ± 0.31 | 421 | 20.05 ± 0.35 | 591 | 21.94 ± 0.38 | 560 |
CBIA-7 high | ||||||||
γH2AX | 2.56 ± 0.13 | 547 | 11.78 ± 0.25 | 534 | 12.41 ± 0.26 | 580 | 12.73 ± 0.30 | 452 |
53BP1 | 1.51 ± 0.07 | 586 | 6.5 ± 0.27 | 415 | 16.9 ± 0.32 | 556 | 17.62 ± 0.34 | 415 |
CCTL-14 low | ||||||||
γH2AX | 4.45 ± 0.20 | 554 | 12.83 ± 0.31 | 544 | 20.99 ± 0.34 | 634 | 30.37 ± 0.57 | 378 |
53BP1 | 2.73 ± 0.14 | 629 | 10.28 ± 0.36 | 508 | 16.77 ± 0.27 | 681 | 19.13 ± 0.39 | 452 |
CCTL-14 high | ||||||||
γH2AX | 6.66 ± 0.29 | 510 | 19.30 ± 0.49 | 427 | 16.26 ± 0.28 | 642 | 19.38 ± 0.34 | 423 |
53BP1 | 4.75 ± 0.21 | 576 | 14.34 ± 0.52 | 402 | 21.49 ± 0.30 | 653 | 24.20 ± 0.42 | 425 |