Fig. 1

Effects of in vivo radiation exposure to a single bone on trabecular and cortical bone of the tibia 12 weeks post-irradiation. a, b Representative reconstructed images of μCT scans showing trabecular and cortical bone in the tibia and (c) tBMD. Differences in (d) BV/TV, (e) BS/BV, (f) Tb.Th, (g) Tb.N, (h) Ct.Th, (i) cortical porosity, and (j) Ct.Ar./Tt.Ar. Data are presented as the means ± standard deviations; ^* P < 0.05 and ^** P < 0.01 (n = 16/group). BS/BV ratio of bone surface to the bone volume, BV/TV bone volume fraction, ratio of the segmented bone volume to the total volume of the region of the region of interest, CT computed tomography, Ct.Ar./Tt.Ar cortical area fraction, Ct.Th average cortical thickness, Tb.N trabecular number, measure of the average number of trabeculae per unit length, Tb/Th trabecular thickness, mean thickness of trabeculae, tBMD trabecular bone mineral density