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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Dysregulated systemic lymphocytes affect the balance of osteogenic/adipogenic differentiation of bone mesenchymal stem cells after local irradiation

Fig. 2

Effects of in vivo radiation exposure to a single bone. a ALP-stained sections showing effect on OB.S/BS at 12 weeks. b TRAP-stained sections showing effect on OC.S/BS at 12 weeks. c Oil Red O-stained sections showing effect on adipocyte area. Data are presented as the means ± standard deviations; ** P < 0.01 and *** P < 0.001 (n = 8/group). d Levels of serum OCN and TRAP at 12 weeks. Data are presented as the means ± standard deviations; * P < 0.05 (n = 16/group). ALP alkaline phosphatase, OB.S/BS osteoblast surface to bone surface, OC.S/BS TRAP-positive osteoclast surface to bone surface, OCN osteocalcin, TRAP tartrate-resistant acid phosphatase

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