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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Dysregulated systemic lymphocytes affect the balance of osteogenic/adipogenic differentiation of bone mesenchymal stem cells after local irradiation

Fig. 3

Changes in differentiation of and relative mRNA and protein levels in BMSCs at 12Ā weeks after irradiation. a ALP, Alizarin Red, and Oil Red O staining of BMSCs. b RUNX2 mRNA expression, (c) PPARĪ³ mRNA expression, and (d) RUNX2/PPARĪ³ ratio. Western blot image (e) and RUNX2 (f) and PPARĪ³ (g) protein expression levels at 12Ā weeks. Data are presented as the meansā€‰Ā±ā€‰standard deviations; * Pā€‰<ā€‰0.05, ** Pā€‰<ā€‰0.01 and *** Pā€‰<ā€‰0.001 (nā€‰=ā€‰6/group). ALP alkaline phosphatase, PPARĪ³ peroxisome proliferator-activated receptor Ī³, RUNX2 runt-related transcription factor 2

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